Alright, here is my problem: My webpage is http://www22.brinkster.com/forthedragon/evahome.html

Feel free to view>>source and check out my scripting. You'll notice the webpage is a mix of layers and iframes. Basicly the menu/main/title/top right picuture are all seperate iframes.

Please look at this link for the source code of my menu:
http://www22.brinkster.com/forthedragon/iframe_menu.html
The problem is in the targeting of the "rants" link in this source code.

See, I want it so that when you click on "rants" the webpage http://www22.brinkster.com/forthedragon/rants/rants.html
I want this page to load in the "main" iframe, however, I cannot seem to get the targeting to work for me.

I know I have the option of simply having the "rants" link reload the entire webpage, but frankly thats not very professional. But I guess considering I can't figure this out I am not very professional, so please, throw me a rope here!

You named your main iframe 'main'... so you should target all of your links (that you want to view in that frame) target="main".

Basically, in your menu, change target="iframemain" to target="main" and target all of your links to "main". HTH.